Cornell.Edu

Description

The faculty within the Department of Microbiology and Immunology pursue diverse projects, but share the concern of how genomes regulate themselves and each other. Our interest in genetic information spans the spectrum from how information can be extracted, understood and applied at the genomic level to how gene products interact at the atomic level. Telomerases, polymerases, recombinases, ligases, and the machinery that processes RNA not only offer powerful experimental tools for diverse fields of medical biology, they are fundamental to the survival of all genomes, and represent potential points of attack against genomes that invade. Immunology is the study of the ability of one genome to detect and reject another. Hosts and pathogens shape each others' evolution, with the immune system as the interface. Study of their interaction lets the accumulated experimental record of evolution serve as a roadmap to significant features of each. Computational biology opens new windows in all these fields.

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